SciELO in Perspective | Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes [

Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes [Originally published in Rev. Soc. Bras. Med. Trop. vol. 53]

04/02/20

By Revista da Sociedade Brasileira de Medicina Tropical

Chloroquine was unequivocally demonstrated to have in vitro inhibiting effects on SARS-CoV-2 infection and was precociously publicized as having a beneficial effect in COVID-19 patients after a study conducted in Marseille, France showed a viral load reduction in COVID-19 patients. Since there is no specific antiviral therapy for coronavirus infections to date, the announcement of partial and fragile data led to precipitated political manifestations by major government leaders and contributed to uncoordinated recommendations of the drug to severe patients. … Read More →

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